Digital Expertise

Software Development

Cloud Services

Big Data


SemanticBits specializes in the design and development of digital health services.

We develop cutting-edge solutions to complex problems for commercial, academic, and government organizations. Our Agile software engineering methodology enables development of commercial-quality products at an affordable price.

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Domain Expertise

Health IT

We excel at delivering IT solutions in the health domain. Our focus is to help you deliver responsive, user-friendly systems to enhance patient care.

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Clinical Genomics

Genomic testing is being used with increasing frequency to help inform treatment. SemanticBits is at the forefront of this burgeoning subfield.

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Clinical Trials

We have a deep understanding of each stage in the clinical trials lifecycle, and we have designed, built, or used systems for every aspect of clinical research.

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Biospecimen Management

We have developed digital services that meet the needs of physicians collecting specimens, biobanking staff managing specimens, and researchers seeking specimens for their studies.

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Our resources have worked in the bioinformatics field for more than 15 years, and the roots of SemanticBits began with translational research software.

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Agile Product Engineering

We follow an Agile development methodology, which emphasizes test driven development, iterative and incremental releases, and user-centered design.

Human-Centered Design

Our Visual Designers and User Researchers incrementally gather information from real people to write User Personas, elaborate User Stories, build wireframes, and design mockups.


We leverage DevOps to implement automation across all aspects of our projects, which allows for automated building, testing (CI), deployment (CD), delivery and monitoring.

Digital Government

We are experts in implementing the USDS Digital Services Playbook and applying USDS and 18F Web Design Standards to deliver and modernize federal digital services.

Latest News

January 10, 2020

2019: The Year in Review

We’re proud to say that it has been a great year at SemanticBits. In 2019,…
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March 14, 2019

SemanticBits-built PRO-CTCAE software is featured in cancer patient research study

The February 2019 issue of the Journal of the American Medical Informatics Association (JAMIA) features…
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March 11, 2019

SemanticBits Launches Facility-Based Score Preview in the Quality Payment Program

SemanticBits is pleased to announce the completion and launch of the facility-based score preview, which…
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February 11, 2019

SemanticBits Wins Recompetition Bid of the Alternative Payment Model Management System

We are pleased to announce that the CMS Center for Medicare and Medicaid Innovation (CMMI)…
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SemanticBits has simply been incredible. Starting with knowledgeable and responsive project management to adept and thoughtful programming, they always figure out a solution to challenges, whether technical or logistical… I couldn’t be more satisfied with their work and would highly recommend them.

Ethan Basch, MDMemorial Sloan-Kettering Cancer Center

SemanticBits’ consummate skill set has made them an invaluable partner in a variety of projects. They were able to take on a large share of the “heavy lifting” quickly and efficiently. Their goal-oriented development model and business style make them a pleasure to work with.

Robert P. AnnechiaricoDuke Comprehensive Cancer Center

The Oncology Clinical Trials domain is highly complex and lacking in standardization. SemanticBits worked with elaborators and early adopters with skill, flexibility most of all, patience. They drew together often conflicting approaches, unnormalized ontologies, and even clashing personalities to deliver software that was accessible and useful.

Bob MorrellWake Forest University Baptist Medical Center

The SemanticBits team has really demonstrated their ability to deliver production quality software very rapidly in the highly complex domain of clinical genomics... In my experience, SemanticBits’ knowledge both in biomedical informatics and software engineering and their agile approach has facilitated robust, informatics application development in both clinical and research environments.

Rakesh Nagarajan, MDWashington University at St. Louis

Clients & Partners